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First, the octapeptide sequences may modulate the toxicity of PrPSc.
Taken together with the results in Figure 7, these data suggest that although the PDZ binding domain is required for the interaction, both the exact sequence of the binding domain and upstream sequences may modulate the interactions of PDZ domain containing proteins.
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These results suggest that inherited sequence variations in XPC may modulate risk of lung cancer, especially lung adenocarcinoma, in Chinese populations.
Selection may modulate gene sequence evolution in different ways, for example, by constraining potential changes of amino acid sequences (purifying or negative selection) or by favoring new and adaptive genetic variants (positive selection).
There is precedent for the idea that sequence-specific differences in DNA adduct structure may modulate NER efficiencies.
Given that kinase and substrate have complementary sequences in a 3D space, stabilization of the activation loop in a certain position may modulate substrate preference by shifting the interactions of the complementary sequences.
Epigenetic changes refer to heritable changes that may modulate gene expression without affecting DNA sequence.
Therefore, we hypothesized that PHGDH may modulate autophagy in ECSLCs.
Calcium and vitamin D may modulate postprandial endothelial function.
In this study, we evaluated to what extend lipids may modulate the MPER immunogenicity.
Combining dietary components may modulate many processes involved in ageing.
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