We compare this genome to the most closely related sequenced fungi, including other pathogens, and find differences in gene content related to cell wall structure and secondary metabolite production.
We demonstrate that, by adopting a data-dependent bucketing scheme and employing a number of encoding ideas, we can achieve substantially better compression ratios than existing de novo sequence compression tools, including other bucketing and reordering schemes.
Similar results were obtained by including other NLR sequences of non-human origin, demonstrating a clear distribution in agreement with the effector domain content.
Concatenation of MUSCLE-aligned GlyRS heterodimer subunit protein sequences sampled across bacterial taxa, including other aaRS outgroups.
Though the video sequences used for the comparison study show a relatively large-scale variation, most of these video sequences also include other attributes.
Interestingly, all of the rRNA genes discovered on the above contigs that mapped near the Nor-B2 locus appeared to be interrupted by other types of genomic sequences, including transposons and other genes.
We therefore recommend that sequencing efforts focus on the exome and, depending on the disease, to extend the targeted sequence to include other annotated elements, as well as regions up- and downstream of genes.
Other flanking DNA sequences, including those derived from other transposed elements (SINEs, LINEs, endogenous retroviruses, and DNA transposons), may also be co-opted into the structure of these ab initio gene candidates.
A full comparison of sequences included in other databases/algorithms versus miRGate is presented in Supplementary Table S1.
