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The gateway, upon reception of all the sequences, estimates the values in the channel matrix.
The model incorporating the ancestral hominin mtDNA sequences estimates the average divergence age of the mtDNAs of Neanderthals and modern humans to be 450,000 485,000 years.
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It was confirmed that several clones had sequences estimated by the LC MS/MS analyses.
In addition, a correlation was found between average block length of 3HB sequences estimated by solution-state 13C n.m.r.
Homologous groups of genes (tBLASTx scores >170) from the other trypanosomatids analysed were also collected into clusters, their UTR sequences estimated using Splicemodel and masked using Tandem Repeat Finder [61], and finally used as input for motif analysis with Trawler.
Due to the limited size of enhancer sequences, estimating higher order Markov models likely results in overfitting and poor estimates.
To identify differentially expressed transcripts, we first filtered the sequences, estimated the transcriptome coverage, and identified expressed genes.
We thus devised an approach that was based on five sequence comparisons among the orthologous and paralogous pairs of sequences estimating d n and d s (fig. 1 C).
We based the measure of relative evolutionary rate on maximum likelihood (ML) trees of nucleotide sequences estimated using the dnaml program [ 74], part of the PHYLIP package [ 75].
This methodology, also called RNA-seq, has been used to analyze unknown transcript sequences, estimate gene expression levels and study single nucleotide polymorphisms (Wang et al., 2009).
Candidate genes for bud phenology related genes (list kindly provided by M. Lascoux & G. Zaina) were searched against peptide sequences estimated by FrameDP.
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