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The format builds on the successful National Center for Biotechnology Information (NCBI) RefSeqGene project and provides a single-file record containing a uniquely stable reference DNA sequence along with all relevant transcript and protein sequences essential to the description of gene variants.
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This exon (exon 2) contains coding sequence essential to functional ADAMTS5 protein as it harbors half of the active site residues.
The NT of Gap1 contains the acceptor lysines for ubiquitylation and its CT includes a sequence essential to exit from the endoplasmic reticulum (ER).
Proteins exported from the cytoplasm through the Sec-dependant pathway contain a short sequence essential to targeting and export.
Because the first variable domain VD1 has been identified as the most likely site for sequences that could control the mode of inheritance of the mitochondrial genome [39], [40], examination of RM-type VD1 sequences is essential to address the hypothesis that these sequences could determine maternal vs. paternal inheritance.
When PCR amplification is performed on groups of closely related sequences, such as the PR-10 gene family, accurate sequences are essential to distinguish between members.
This is reasonable because mature sequences are essential to recognize target genes as well as to make a duplex structure with star sequences, whereas star sequences appear to be essential only for keeping the duplex structure with mature sequences.
Since gene duplication is a straightforward method for achieving dosage compensation of a haploinsufficient gene, implementation of short-read sequence analysis tools that are inclusive of limited multiply-aligned sequences is essential to generating the most biologically realistic RXE levels.
In view of the limited number of COI sequences available for marine nematodes, a strict quality control of the obtained sequences is essential to build a reliable reference database.
High-quality data about protein structures and their gene sequences are essential to the understanding of the relationship between protein folding and protein coding sequences.
The specific placement of each element in the sequence is essential to the sequence's function (consider, for example, the "syntactic chain" in rodent grooming behaviour, Aldridge and Berridge 1998; Berridge et al. 1987).
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CEO of Professional Science Editing for Scientists @ prosciediting.com