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Deletion mapping of Sindbis virus DI RNAs derived from cDNAs defines the sequences essential for replication and packaging.
To maintain stability, these targets were incorporated in multiple locations within the 3′-untranslated 3′-untranslatedg sequences essential foregionl replication without aflanking the viral open reading frame.
The single open reading frame is located between two untranslated regions (UTRs), the 5' UTR and the 3' UTR, which contain RNA sequences essential for RNA translation and replication, respectively [26 28].
It is tempting to speculate for instance that Retrotransposons -rich rye heterochromatic domains when present in triticale loose their capacity to remain condensed, allowing for the occurrence of changes in retrotransposon and microsattelite flanking sequences, essential for polyploid stability.
In this scenario, our observations imply that the key cis-regulatory sequences essential for SHM targeting reside in non-coding regions of the Igκ locus outside these well characterized transcriptional control elements.
Aldehyde dehydrogenases (ALDHs) are a group of proteins that share highly conserved sequences essential for function.
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These proteins contain an N-terminal transit peptide sequence essential for apicoplast targeting during which the P. falciparum Hsp70-1 plans an important role.
Using pyrazinone analogs and aliphatic amino acids instead of the disulfide bond, we prepared novel type somatostatin analogs including the sequence essential for antitumor activities, Tyr-d-Trp-Lys.
A functional polymorphism located at −1 from the start codon of the CD40 gene, rs1883832, was previously reported to disrupt a Kozak sequence essential for translation.
Phosphorylation of tyrosine 1176 Tyr11766), a residue adjacent to the RSLESD sequence essential for 14-3-3 14-3-3 14-3-3bindingown to prevent binding of L1 to thasAP-2 adaptor protein, therebeenlocking L1 endocytoshown49].
The iTol2 cassette enables incorporation of the Tol2 cis-sequences essential for transposition into a BAC clone through a single step of homologous recombination.
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