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Differences in the sequences could affect, for example, how likely a person is to have heart problems or suffer side effects from a cholesterol drug.
The selective binding of them to DNA sequences could affect the interactions of transcription factors with their target sequences in DNA.
The difference in sequence depth within the position-tags is therefore more likely an effect of primer qualities in combination with the fact that different tag sequences could affect the primer annealing by forming secondary structures.
Moreover, small variations in the mannopeptide sequences could affect the substrate specificity of POMGnT1.
Whether variations in individual sequences could affect this contact such as charge and polarity changes in loop 2 of AtXI-J or the phosphorylatable threonine residue in class XI myosins [ 23] and in DdMyoJ can not be predicted.
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Therefore, it is not surprising to raise the question whether the use of different endocrine adjuvant therapies in sequence could affect the clinical outcome.
Switching of the spacer sequence could affect promoter strength by changing the curvature of promoter DNA, which, in turn, may influence the recognition of the −10 element or RNAP contacts with downstream DNA (Hook-Barnard and Hinton, 2009).
The presence of the target sequence upstream or downstream of the precursor sequence could affect both host gene post-transcriptional regulation as well as miRNA regulation or self-regulation in the case that the target site belongs to the same miRNA family as the miRNA precursor.
Five clones, including SO3896, contained errors in the oligo-encoded 5' or 3' adapter att sequences that could affect the frequency of subsequently recombination into destination plasmids.
Note that this quantification of transposable element abundance could have been underestimated by the shortness of the RAD tag sequences which could affect search sensitivity.
To evaluate whether sequence divergence could affect exome capture, especially in a mixed genetic background, we performed exome sequencing on a F1 hybrid mouse derived from crossing C57BL/6 J and SPRET/EiJ mice using an Agilent SureSelect XT Mouse All Exon Kit (Methods).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com