Exact(1)
Even among codifying sequences, constraints act differently depending on the effect a possible mutation will generate on gene product.
Similar(59)
Improved tightening and sequencing constraints have been presented.
We investigated the sequence constraints associated with the RA signature using several artificial self-assembly systems.
An encoding strategy of every particle was invented for handling the serial task sequence constraints.
The partial conformation allows users to specify both the structural and sequence constraints for each state.
This architecture has one pathway for mapping message content to words and a separate pathway that enforces sequencing constraints.
Without the explicit modeling of these sequencing constraints, a scheduler is often not capable of finding a solution that satisfies the timing and resource constraints.
We propose improvements in allocation, duration and sequencing constraints, and investigate the effect of big-M terms in several constraints to enable solution of large-scale problems.
We also show that such analysis can establish structure/sequence links by providing the sequence constraints necessary to encode designable motifs.
This follows the biologically relevant motivation, which is to identify RNA structural characteristics that are subject to sequence constraints and that thus relate RNA architectures to sequences.
In addition, a proper formulation of the sequencing constraints provides a substantial saving in the number of sequencing variables and constrains.
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