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Regulatory sequences can influence the expression of flanking genes over long distances, and X chromosome inactivation is a classic example of cis-acting epigenetic gene regulation.
A few recent studies using DNA in NP synthesis reported encouraging findings that different DNA sequences can influence both the structure and property of the nanomaterials.
CTT sequences can influence subcellular localization of different MT arrays, interactions with plus-end tracking proteins (+TIPS) that influence dynamic instability, and sites for motor proteins to preferentially bind [ 41].
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Mechanical testing further shows that the stacking sequence can influence the failure significantly.
Construction sequencing, including pour sequencing, can influence cracking (Hadidi and Saadeghvaziri 2005), as do vibration techniques, weight and vibration of construction equipment, and deflection of formwork (Issa 1999).
Recent studies have reported that the oscillations of auditory attention entrained by a background rhythmic sequence can influence performance in visual recognition tasks.
The crystal structure of the T3-785 peptidemonstratesthatthat sequence can influence local conformational changes in triple-helical structure, in terms of superhelical pitch, hydrogen bonding pattern, and hydration patterns.
Further experiments also indicate that local DNA sequence can influence the choice of the target site [6].
Flanking sequence can influence the interaction of some transcription factors with DNA, for example, the interaction of the E2F family with DNA is influenced by a region of at least 8 nucleotides 5' and 11 nucleotides 3' to the central nucleotide [50].
In addition, by studying the binding to Diva of Harakiri constructs of different length we identify the critical region for binding in Harakiri and observe that affinity increases for constructs longer than this region, suggesting that the flanking sequence can influence binding.
The use of a flanking sequence can influence IDP aggregation.
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