Sentence examples for sequences can disrupt from inspiring English sources

Genomic variants in splicing regulatory sequences can disrupt splicing and cause disease.

Failure to remove such abundant contaminant sequences can disrupt the assembly process (due to the high read depth compared with the nuclear genome) and may result in the production of chimeric and contaminated contigs.

In addition the Cre-recombinase based system leaves behind within the ORF a peptide sequence coded for by the remaining loxP site, a sequence that can disrupt activity (unpublished).

Recognition of the BPS is thus a crucial step in proper splicing, and sequence variants can disrupt this event, impede lariat formation, and intron excision.

Blockchains can disrupt the disrupters like Uber.

TEs can disrupt host sequences and serve as substrates for homologous recombination, generating DNA rearrangements such as deletions, duplications, inversions, and translocations (Burns and Boeke 2012).

Similarly, mutations can disrupt other sequence-specific regulatory controls, such as elements regulating RNA splicing or stability.

The insertion of a CREE can generate a promoter at either its the 5' [ 36] or 3' end [ 37] and can disrupt the sequence into which it has been inserted.

The resulting steady state fluxes and concentrations, as well as dynamic responses to the perturbations were analyzed, yielding two important conclusions: 1) that transporters are informative about the internal states (fluxes and concentrations) of a cell and, 2) that genetic variations can disrupt the natural sequence of dynamic interactions between network components.

Thus, only viral escape mutations at I14, P16 and F20 can disrupt neutralization mediated by 3074, while sequence variation elsewhere in the V3 loop leaves the interaction unaffected.

As structural variation can disrupt genes or regulatory elements, whole-genome sequencing without assembly and detection of structural variation produces an incomplete picture of the genome.