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This effect is disconcerting as merely changing the order of the sequences can change the alignment.
DNA sequences can change through mutations, producing new alleles.
Like DNA, protein sequences can change over time.
This finding suggests that host PrP sequences can change the phenotype presentation of the agent in the host and could thereby confound identification of cross-species transmission events.
These sequences can change the spacing between DNA elements, which can have undesirable effects on the structure and activity of fusion protein and interfere with accurate analysis.
Similar(55)
Synonymous substitutions of single codons without changes in the primary amino acid sequence can change substrate specificity, viral virulence, or protein expression levels [17] [19], probably due to altered speed of translation and indirect on the folding fidelity.
Loosely put: "sequence can change without effect".
Mitochondrial DNA (mtDNA) is exclusively maternally inherited, thus different mtDNA lineages cannot mix or recombine: the only way that the mtDNA sequence can change is by the sequential accumulation of mutations along radiating maternal lineages.
Note that conventional NAND Flash memory devices provide command sequences that can change the SRVs.
Mobile element insertions (MEI) refer to insertion of sequences that can change their position within the genome.
Transposable elements are generally non-coding DNA sequences that can change its location within a genome and can play an important role in development and evolution [ 13].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com