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However, the complexities of the relationships between sequences and traits and from traits to disease phenotypes, make the prediction of pandemic potential from genomic sequence a tremendous challenge.
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This unexpected finding derives from recent studies that measure the association between genotype (variations in DNA sequence) and traits (e.g. height or disease risk) among large populations of unrelated people.
We will also incorporate interactive tools that can be used by root and bulb researchers to annotate sequences, phenotypes and traits, and to submit linkage maps, markers, molecular phylogeny data, pathways and other relevant data types which are of interest to the user community.
Recent work has illuminated some of the structural properties of Yule trees, but it remains mostly unknown how these properties affect sequence and trait patterns observed at the tips of the phylogenetic tree.
The PGP aims to collect data on a person's DNA, environmental background, and relevant health and disease information from consenting participants and make them publicly available to scientists who study the relationship between specific DNA sequences and various traits.
With her research focusing on genome evolution and the relationship between DNA sequences and biomedical traits, Pollard's work has important implications for how science identifies and treats a wide range of diseases, from AIDS to atherosclerosis.
For example, nucleotide sequences and morphological traits can be readily assessed together as characters, but it is not generally possible to include nucleotide sequences and genetic distance data in a single analysis [ 34].
Genomic sequencing of crop species has shed light on causative relationships between sequence polymorphisms and traits of agronomic interest.
Genome-wide association studies (GWAS) are a commonly used study design for identifying associations between commonly occurring variations in DNA sequence and human traits.
Within three days of project commencement, draft genome sequences were available that were suitable to begin comparative analyses such as genome alignments, preliminary annotation of coding sequences, and identification of traits associated with macro-diversity and micro-diversity.
When classification accuracy (CA) is less than 100%, it is important to distinguish fundamentally unclassifiable cases (e.g., recently acquired sequences and slowly evolving traits) from boundary cases that could be distinguished by using a better classifier.
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