Sentence examples for sequences and compounds from inspiring English sources

The receptor sequences and compounds are assigned predictor variables that are correlated to the measured pharmacological activities using partial least-squares projections to latent structures.

In the present study, an efficient synthesis of some new substituted pyrazoline derivatives linked to a substituted pyrazole scaffold was performed by a multistep reaction sequences and compounds were screened for their anti-inflammatory, analgesic and antibacterial activities.

The NNRTI set represented a different data set compared to the GPCR ligand dataset evaluated above, as it consists of a number of highly similar sequences and compounds and, hence, resembles a typical data set one might encounter in lead optimization.

This case study illustrates the versatility of camb to train and validate PCM models from amino acid sequences and compound structures in an integrated and seamless modelling pipeline.

Laarhoven et al. described the targets and ligands by sequences and compound 3D structures respectively, and introduced the target-ligand interaction network to build the prediction model [ 10].

Moreover, LBD sequence and compound SAR analyses provide support to the utility of these qHTS assays in their ability to identify known endocrine-disrupting environmental chemicals and revealed classes of chemicals with activity patterns that could serve as bases for in-depth toxicological testing prioritization and provide clues for toxicity mechanism interpretation.

Quantitative PCM models were then trained on a dataset comprising 20 eukaryotic, protozoan and bacterial DHFR sequences, and 1,505 distinct compounds (in total 3,099 data points).

Patent protection by agri-business companies now covers many of their genes and gene sequences, compounds and properties.

We performed whole exome sequencing and identified compound heterozygous GMPPB mutations in the affected children.

DNA sequences were visually inspected to identify perfect and compound microsatellite sequences and PCR primers specific to each locus designed using the program fastpcr [43].

In the context of protein identifiers within databases the important utility of being able to perform BLAST searches against the actual sequences (and link back to compound data) is currently limited to DrugBank, BindindDB and the protein targets in PubChem BioAssays.