"Since that time we've reduced the cost so fast for sequencing this information that they call it Flatley's law, after Illumina's CEO Jay Flatley," Cashin says.
In the case of GBS markers, for species without a reference genome sequence, this information is presumably lacking and consequently construction of a de novo linkage map is a tedious job.
Because the optic radiation and its anterior extent could not previously be visualized with conventional, clinical MRI sequences, this information was not incorporated into studies investigating the relationship between MRI based volumetric assessment of resection size and VFDs.
Over a decade after the human genome was sequenced, what has this information delivered?
In spite of increasingly high throughput sequencing technologies, this information is not available for every microorganism and rarely available for entire microbial communities.
For the remaining 69 isolates, species/clade identities were different with each sequencing method (this information is provided in Additional file 1).
The structure presented provides a structural explanation for all loss of activity mutations covered in the sequence, although this information was not used for model generation.
For sequences without this information, we used NetPicoRNA [ 30] to predict the polyprotein cleavage sites and then manually curated ambiguous boundaries.
The inclusion of sequencing to yield this information in future studies would be informative.
