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All viable JCV genomes contain a conserved region in the T protein coding nucleotide sequence that when detected by PCR in CSF is a confirmatory diagnostic marker for PML along with clinical and neuroradiological evidence.
This sequence corresponds to the proposed Forkhead sequence that, when combined with an EBS, is suggested to be important for the regulation of genes in endothelial cells [13], [14].
One method to produce this dsRNA is to introduce into cells a DNA sequence that, when transcribed, forms a hairpin that is primarily double stranded.
Conversely, a gene that is not as active in transcription may have a sequence that, when bound by berenil, adopts a conformation that attracts a positioned nucleosome and makes a transcription factor binding site available, up-regulating transcription.
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If you wrap the elements of concept, hero, villain, and world/setting into that opening action sequence, that's when you'll truly engage the reader/audience.
The resulting output was a sequence of parameters that when streamed to the CI would produce a corresponding sequence of stimulation.
McHugh played in the victories over Wigan and Arsenal as well as both legs of the tie against Villa, a spectacular sequence that was inconceivable when the Irishman was released by Reading last season.
The dream sequence that is instigated when Rey touches the Anakin's old lightsaber is difficult to follow, particularly the audio.
The grainy, scrapbook-inspired credit sequence that plays out to "When I Grow Up (to Be a Man)" by the Beach Boys, with its tenor of preordained wistfulness, sets the mood at the proper caliber of restrained bittersweet sentimentality.
Insulator elements are DNA sequences that, when bound by insulator proteins, are thought to play a key role in chromatin organization by mediating intra- and interchromosomal interactions.
Several methods [ 8- 12] have been developed to identify conserved non-coding sequences that, when tested, often function as regulatory sequences in vivo (reviewed in [ 13]).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com