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Probe activation and cargo uptake depend on localized proteolysis of the linker sequence that connects the polyanionic and polycationic domains, which converts the probe to an adherent form.
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Bridge accepts two probe sequences as input and searches the set of RNA-seq data for a continuously expressed spanning sequence, if any, that connects the two probe sequences.
The incompatible alanine-to-valine substitution in the Aatm Ore allele is adjacent to the conserved "KMSKS" sequence in a loop that connects the binding and catalytic domains.
But it is the annotation that connects the sequence to the biology of the organism [ 4].
Given the sequences in which the word occurs, the BLS can be calculated by finding the minimum spanning tree that connects these sequences in the phylogenetic tree.
We confirmed this by PCR-amplification and sequencing of a 1,651-bp 1,651-bp that connects the 3' large repeat ofragment077 withathe gene enconnectshe calmodulin-binding prothen.
The MJN method begins computing the minimum spanning trees (a graph that connects all the sequences with the minimum necessary total length of the branches), following which all the constructed graphs are combined within a single (reticulate) network.
For IME-EFm1, the sequence GGGTCAGCG is the 9 nt tail that connects 5′ and 3′ ends.
For IME-EF4, the sequence TCATCACCG is the 9 nt tail that connects the 5′ and 3′ ends.
The connectivity module is based on molecular topology, which adequately describes the sequence of bonds that connect atoms in the molecule.
Results proven include finding a sequence of paths that connect a given pair of nodes throughout the system, such that the global routing plus re-routing costs are minimized.
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CEO of Professional Science Editing for Scientists @ prosciediting.com