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We also thank Raju Tomer for his help with Platynereis sequence submissions.
First, they are a shared resource, and one may be limited to a small number of sequence submissions in a given amount of time.
It is important to point out that our evaluation of these systems is benchmarked against genes from associated GenBank sequence submissions spanning a wide range or organisms.
Whether due to recent sequence submissions [ 47], or through the challenges of assembling large EST datasets in individuals with recent genome duplications [ 48, 49], a few annotations of differentially expressed genes varied from the originally released 16K annotation file [ 50].
Although all the strains of HEV have complete genome sequences, there are also many partial sequence submissions for each strain in GenBank that were ignored for the HEV design.
Tel: +81 559 81 6853; Fax: +81 559 81 6849; Email: http://[email protected] (for data submissions); http://www.ddbj.nig.ac.jp EMBL: EMBL Nucleotide Sequence Submissions, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
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Sequence submission to GenBank pending manuscript acceptance.
Predicted picornavirus cleavage sites were identified by amino acid sequence submission to the NetPicoRNA World Wide Web server [54].
We are grateful to Dr. Chen Chen, Dr. Haiyin Wang for the help of the sequence submission to GenBank and Dr. Yiting Wang for the discussion of the plasmid comparative analysis.
A recent sequence submission may improve on and outdate previous annotations for only one member of a protein family, but the other members might not benefit from this acquisition.
This study could be performed retrospectively, since sequence submission dates are easily obtained from public databases.
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