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DNA cleavage occurs at a 2 bp crossover sequence site has been demonstrated in both phiC31 and Bxb1 integrases [26], [27], [28].
For mRNA microarray, the probe(s) for each gene can be designed at the unique DNA sequence site on the gene to avoid the cross-hybridization.
Branch lengths express the number of amino acid substitutions per protein sequence site.
However, this method is known to introduce bias due to factors that might impair the activity of sequence site recognition.
Of the 100 CDSs inspected, 10% had their 5′-end confirmed by the presence of a TSL sequence site.
Besides the RGD-like sequence site should be placed on a loop or a beta-turn to be well exposed.
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To determine all the potential CRISPR sites in the human genome, we used a custom Perl script to search both strands and overlapping occurrences of the 23-mer CRISPR sequence sites GN19NGG or AN19NGG.
To understand the effects of mutation at the GGEEF signature sequence, site-directed mutagenesis using the mega primer method was utilized to generate three mutants Sebox5, Sebox6 and Sebox7 representing mutations at the second G, first E and the second E, respectively.
We developed a statistical technique for modeling the correlation structure in variable DNA sequence sites.
BACKGROUND: A significant challenge in bioinformatics is to develop methods for detecting and modeling patterns in variable DNA sequence sites, such as protein-binding sites in regulatory DNA.
Conservation of short sequence sites can be assessed using different metrics.
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