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These profiles were manually edited to produce global matches on the profile side and local matches on the sequence side.
The variant information is displayed in the general context of the whole sequence, side by side with the annotation of domains, post-translational modifications, and secondary structures.
The same approach of data generators actively engaging with speeding up and improving the transfer of their own results into databases applies equally to the sequence side of things.
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Any mAb contacts with peptide main-chain atoms are not included in the motif, as these are not sequence (side-chain) specific, and viral escape mutations that change the side chain will not necessarily alter the backbone or the mAb interaction.
If we make comparisons between any two human genomic sequences side by side, they will be almost 99.9%% identical [ 2].
The program first performs pairwise alignments between all pairs of sequences, lining up the sequences side by side to identify the regions of similarity and difference between sequences.
On the sequencing side, real-time, single-molecule sequencing has been achieved by Pacific Biosciences, and Oxford Nanopore has promised to deliver a mobile, disposable sequencing device the size of a thumb-drive [ 6].
Since all pure GA-sequences of a chromosome are lined up in tandem on the same DNA strand, there is essentially only one non-disruptive way of forcing all of them into a small space, namely by placing the pure GA-sequences side-by-side while folding the intervening stretches of DNA between them into loops (See Fig. 5, Fig. 6).
Three types of thermally coupled distillation systems, namely the sequence with side rectifier, the sequence with side stripper and the Petlyuk column, have been shown to provide significant energy savings for the separation of ternary mixtures with respect to the conventional direct and indirect sequences.
At three separate locations in the 160-nucleotide domain, adjacent adenosines in the sequence lie side-by-side and form a pseudo-base pair within a helix.
This program computes the correlation coefficient of pair wise distances between the target sequence and all other sequences on both sides of a sequence position.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com