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But the data have not been placed in any public sequence repositories.
Database technology has enhanced and diversified these resources into more than mere sequence repositories.
As a consequence, genome sequence repositories and databases worldwide have developed dramatically to incorporate these large volumes of sequence data.
DNA-based identification methods benefit from large, public, DNA sequence repositories, and many openly accessible or downloadable analysis tools.
Selection of candidates from sequence repositories is facilitated by the monophyletic relationship among biosynthetic genes belonging to a wide range of enzyme families, such as the numerous cytochromes P450 and AdoMet-dependent O- and N-methyltransferases that operate in BIA metabolism.
Our computational analysis of sequence repositories has identified another 4 potentially novel V-ATPase variants.
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This sequence repository has been used to design custom CHO Affymetrix arrays for transcriptome analysis.
Since 16S rDNA sequence repository is quite large, we focused our studies on this gene.
Comparing the non-drug target group of GPCRs with the GenBank patented sequence repository showed that 537 genes (80%) had patents associated with them.
The course of action is straightforward: some predefined DNA region of the organism is sequenced and compared for similarity in an inclusive database for sequence data such as the longstanding International Nucleotide Sequence Database [3] (INSD: GenBank, EMBL, and DDBJ) which is the most widely used sequence repository in the field.
This study involved the analysis of three datasets: a quantification of all detailed longitudinal escape events reported in the literature (21 events in 15 distinct epitope-alleles), analysis of the functional CTL response in 150 HIV-1 infected individuals and analysis of sequence variation in clade B HIV-1 sequences from the Los Alamos National Laboratory (LANL) Sequence Repository.
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