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Others discussed tweaking the RNA portion of CRISPR so that it will more accurately home in on the desired sequence, reducing "off-target" effects.
The use of an SE sequence, reducing the echo time and increasing the acquisition matrix, may be helpful to minimise these susceptibility artefacts.
An ASO targets a specific mRNA sequence, reducing its expression [ 4– 6].
Analysis of possible mechanisms of E-cadherin up-regulation revealed that butyrate induces the release of nuclear proteins from the E-cadherin promoter sequence, reducing transcription repression.
The frameshift detected in mutIV-mix-2 inserts a stop codon early in the sequence, reducing the protein to just 38AA.
Thus, reads were filtered, not only based on quality, but also on presence of adaptor sequence, reducing the data set to 33,185,901 fragments that was used in de novo assembly (∼15 million where paired end sequences were retained and ∼18 million when only one of the paired reads was retained).
Similar(53)
The presence of training symbols in the data sequence reduces the spectral efficiency and power efficiency of the transmission.
Results indicate that repeating cereal crops in the cropping sequence reduces their productivities, while well balanced sequences that include legumes resulted in the highest productivities of cereal crops.
In the case that all the subsets A i ⊂ X intersect, the above limit sequence reduces to a unique fixed point allocated within the intersection of all such subsets.
Mutating the XRE-like motif to a non-XRE sequence reduced basal promoter activity by 85% and reduced maximal AhR/ARNT-induced promoter activity by 86% relative to the wild type αB-crystallin promoter activity (Fig. 10).
Deletion of P2 and P3, alone or together, or replacement of the first 21 residues of each period with a GCN4 leucine zipper sequence reduced actin affinity but did not destroy binding [32], [34], [36].
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CEO of Professional Science Editing for Scientists @ prosciediting.com