Beyond sequence preference, chromatin features dictate the repertoire of these genome-modifying enzymes.
The structural basis of the amyloid formation and the sequence preference are unknown.
There is limited evidence to suggest a slight GC sequence preference.
No clear sequence preference was observed, similar to previous observations with the isolated PWWP domain of Dnmt3b but with one order of magnitude weaker affinity.
The results are used to determine drug binding sites and sequence preference, as well as conformational changes due to drug DNA interactions.
The 2935 motifs were assigned k-mer scores reflecting the degree of sequence preference with respect to 3-mer (n = 64) and 4-mer (n = 256) words.
Apparently the star activity of DraIII has a sequence preference for the central three nucleotides, whereas the canonical cleavage activity does not (Grosskopf et al., 1985).
UV/visible absorbance, circular and linear dichroism spectroscopies have been used to characterize the interactions of the cylinders with DNA with the aim of investigating any sequence preference or selectivity upon binding.
The strong correlations and the sequence preference involved in the protein structures make this fuzzy architecture based model as a suitable candidate for building profiles of a given family, since the fuzzy set can handle uncertainties better than classical methods.
Within the context of CATNNNGTG, the DraIII star activity has a sequence preference for the central three nucleotides, whereas the canonical cleavage activity does not (Grosskopf et al., 1985).
Retroviral integration sites display a subtle sequence preference unique to each virus [42], [43].
