They share a conserved sequence pattern and catalyse the displacement of CMP from a CDP-alcohol by a second alcohol.
The hallmark of most coiled coils is a regular sequence pattern known as the heptad repeat.
Members of this family are integral membrane proteins that share a conserved sequence pattern and usually comprise 150 400 amino-acid residues.
We therefore propose to add this first aspartate residue in the consensus sequence pattern of CDP-OH phosphotransferases, as previously suggested25.
Site-directed mutagenesis on conserved amino-acid residues from the family sequence pattern or considered functionally relevant (for example, for substrate binding) was carried out.
Genomic studies revealed the sequence pattern and identified highly conserved residues that catalyzed the reaction in protozoan parasites.
Finally, by taking a sequence pattern similarity measurement and applying condensed hierarchical clustering methods, the routine pattern is distinguished.
Our designer peptides employs a sequence pattern that undergoes salt triggered self-assembly into β-sheet rich cationic nanofibers in the full pH range (pH 0 14).
The task of sequence pattern discovery, also known as motif discovery, is to uncover these unseen subsequences ab initio and then build a motif model for them.
Traditionally, sequence pattern mining has been used to mine items occurs in time sequences and items were deemed to be irrelevant to each other.
Through a computer search procedure designed to detect shared, yet degenerate sequence features, we have identified a conserved sequence pattern upstream of Saccharomyces cerevisiae tDNAs.
