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The sequence relied on a DWI sequence optimised for foetal imaging, modified to accommodate more b-factors within a clinically feasible imaging time.
Even if 3D double-echo steady-state sequence optimised for cartilage imaging improves lesion conspicuity, it doesn't seem to improve diagnostic performance [65].
Data were acquired using a sequence optimised to reduce susceptibility artefacts near air/tissue interfaces (Weiskopf, Hutton, Josephs, & Deichmann, 2006).
In our hands, highly sequence optimised AAV-MDs are available for use in mouse, dog and humans, expressed using a strong skeletal and cardiac muscle specific synthetic promoter, have been tested in detail in mdx mice, and in the GRMD dog.
Obviously, modifying the sequence by adding a sequence optimised peptide tag also avoids expression problems associated with the inition of translation.
We therefore studied a large sample of patients and a carefully matched control group using a sophisticated acquisition sequence, optimised for the study of white matter, 8 and a voxel-based method of analysis specifically developed for DTI data.
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While confirming the potential benefits of combination treatments, preclinical studies have also underscored the importance of dose, schedule, and sequence to optimise the putative additive effects of combination approaches and to prevent possible negative inhibition (Siemann and Rojiani, 2002b; Wachsberger et al, 2005).
In Street Fighter, command inputs usually combine specific movements of the joystick, more often in quarter or half-circle revolutions, followed by button presses – but these must often be deployed in complex sequences to optimise the attacks.
This result further suggests that individuals incorporated information extracted from the food call sequences to optimise their foraging strategies, in some cases against pre-existing foraging biases.
It can be synergistically combined with Sanger sequencing to optimise detection of rare mutations.
Moreover, 'Advanced WARP' according to our results is more effective in reducing metal artefacts even in comparison to conventional MR techniques suggested in case of disturbing foreign bodies with increased susceptibility (using shortening of TE, avoiding gradient-echo pulse sequences or optimising bandwidth [ 18– 20]).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com