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A blocking tail captures a part of these sequences in the stem region of the hairpin.
This assumption creates a trivial computational problem where the sequence on one side of the stem can pair with only one other sequence, a problem solved by many existing algorithms (e.g. string matching algorithms).
This similarity between stems is captured based on features like stem length, sequence, stem stability, loop sequence closed by the stem and so on.
To quantify miR156b, primers based on the stem sequence of the pre-miR156b hairpin structure were designed to measure premature miR156b according to Schmittgen et al. [ 57] (Additional file 5).
Firmly grasp the stem of the strawberry.
Cut the stem of the banana off.
Pick off the stem of the cherry.
Locate the stem of the blood feather.
The resulting GYIGSR-immobilized EVAL (EVAL GYIGSR) membrane was analyzed in terms of the effect of immobilized peptide sequence on the behaviors of neural stem/precursor cells (NSPCs), isolated from embryonic rat cerebral cortex, in the serum-free medium.
Peptides based on the sequences of the stem region (residues 419 to 447) of all dengue serotypes showed cross-reactive antiviral activity (IC90: 0.1 μM–>6 μM), although similar peptides from other flaviviruses are not effective against dengue viruses [ 86].
Moreover, sequences on the extended Stem I also mediate tertiary interactions within the RRE.
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