Exact(3)
We propose a simple mnemonic and classification to facilitate description of spinal degenerative changes by dividing them into three categories of A, B and C changes, based on the location and sequence of progression.
A predictable sequence of progression of lesions facilitates a staging strategy that can be followed when assessing neurodegenerative lesions (3, 5, 17).
Results of a statistical analysis of the patterns of co-occurrence of these lesions in wild English sole are consistent with the concept that these lesions represent morphologically identifiable steps forming a sequence of progression ultimately leading to the development of hepatic neoplasms.
Similar(57)
The six exercise sessions presented within the other two DVDs are comprised of an orchestrated sequencing of progressions (ie, beginning with simpler, more basic movements, and then building on exercises learned to ultimately engage in more complex movements).
The four bar sequence of the progression continues and features instrumentation from guitars, electronic handclaps, cowbell played by Madonna, and a synthesized string arrangement.
Significant features of hα-syn spreading in rats include (i) the targeting of preferred anatomical sites, (ii) a consistent sequence of histological progression, and (iii) bilateral but asymmetric brain burden.
Also, the development of such autoantibodies occurs relatively early in the sequence of disease progression and makes targeting those enzymes responsible for such PTMs an attractive potential therapeutic intervention.
The IPCL classification for oral squamous epithelium was created by dividing the findings into type I (normal mucosa, regular brown dots), type II (IPCL pattern dilation and crossing), type III (IPCL pattern elongation and meandering) and type IV (IPCL pattern destruction and angiogenesis following a sequence of carcinogenesis progression) [ 10].
During the initial sequences of metastatic progression, cancer cells originating from the primary site intravasate into the lymphatics and systemic circulation as circulating tumor cells (CTCs) [ 11, 12].
These results suggest that zebrafish cancer models, coupled with transgenic zebrafish reporter lines, are powerful tools for the analysis in vivo of the initiating events of pancreatic tumorigenesis and the sequences of hallmark progression during cancer development.
Recently, other genetic tumour models with similar sequences of disease progression have been described, such as conditional liver-cell specific knockout mice of the TNF-dependent signaliver-cell specificd Taknockout 197] or mice with hepatofythespecific overexpression of the proinflammatory cytokine lymphotoxin [ 198].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com