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Secondly, we redefined treatment status by using a three month cut-off (that is, the treatment period was defined as a sequence of prescriptions without discontinuation within 92 days).
As in previous studies, 22 23 we defined a treatment period as a sequence of prescriptions for ADHD drug treatments with less than six months (183 days) between two consecutive prescriptions; we considered gap of six months or more between prescriptions to indicate a non-treatment period.
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Firstly, the ascertainment of treatment period was based on a sequence of dispensed prescriptions that might inaccurately reflect the actual consumption of drugs by patients, because other family members or healthcare staff could also pick up the drug.
In our study, sunitinib was the most popular first-line therapy, but the diversity of first-line and second-line therapy choices indicates that the sequence of TT prescription may be practice-dependent.
Partial filling of prescriptions.
Manner of issuance of prescriptions.
§ 1306.23 Partial filling of prescriptions.
§ 1306.05 Manner of issuance of prescriptions.
Labeling of substances and filling of prescriptions.
21 CFR § 1306.23 - Partial filling of prescriptions.
Rates were calculated as number of prescriptions per 100,000 people.
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CEO of Professional Science Editing for Scientists @ prosciediting.com