Sentence examples similar to sequence of intrinsic from inspiring English sources

Sequencing of intrinsic blaVIM confirmed that the nucleotide sequences obtained were identical to genes for VIM-2 for P.aeruginosa.

In addition to hDBC1 and hCCAR1, we determined the sequence level of intrinsic disorder from other species using a CH-CDF plot.

We conclude that regardless of the exact approach used to infer sequence determinants of nucleosome positioning, models of intrinsic nucleosome sequence affinity should not be trained on in vivo datasets as their nucleosome distributions may be affected by other factors and the extent of the influence of these factors varies with the details of the computational algorithm.

Our findings highlight the importance of both sequence specificity and active nucleosome repositioning in creating large-scale chromatin domains, and the antagonistic roles of intrinsic sequence preferences and chromatin remodelers in C. elegans.

Our results yield quantitative insights regarding the relationship between sequence and the degree of intrinsic disorder within bZIP-bRs, and might have general implications for other intrinsically disordered proteins.

This illustrates that our approach may be used to better understand the importance of intrinsic sequence preferences for achieving specificity within TF families.

37i This quality of the DNA substrate allowed the authors to examine the influence of intrinsic sequence content on the nucleosome binding landscape in the absence of any other factors.

Characterization of intrinsic sequence preferences (i.e., those due only to the TF interacting with the DNA) ideally involves either in vitro or heterologous systems [ e.g., bacterial 1-hybrid (Meng et al. 2005)], to avoid confounding effects of other factors present in the cell.

Here, we apply a computational model of intrinsic nucleosome sequence preference [1] to the human genome.

Significant disruptions of intrinsic nucleosome sequence preferences in C. elegans in vivo have been previously reported [ 22, 26].

However, in contrast to the HMRs within CGIs, the nucleosomes at the boundary of non-CGI HMRs are predictable by a model of intrinsic nucleosome sequence preference (intrinsic nucleosome occupancy scores (INOS)) [ 33] suggesting that the localization of nucleosomes at these boundaries might be driven by DNA sequence.