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To a large extent this has been associated with lack of any particular need to equate the usual sequence of inflammation and repair that accompanies the introduction of biomaterials into a host site with the innate immune response, even though the main cellular and humoral features of the latter were usually evident in the former.
Rotator cuff healing occurs via a sequence of inflammation, repair, and remodeling [ 21].
On the other hand these findings might also be compatible with the chronological sequence of inflammation followed by fibrosis processes.
Normal wound healing involves a sequence of inflammation, proliferation, and maturation or remodelling [12] and local IGF-I production increases as wound healing progresses [35].
We used a special modern CMR sequence of inflammation (STIR) which has been used to detect cardiac inflammation in previous studies [ 23– 25, 40], and is recommended in a recent consensus paper [ 41].
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When these pressures exceed the capillary-arteriolar blood pressure (ca 30 mmHg) tissue ischemia can lead to a sequence of inflammation-ulceration-granulation and stenosis.
Rodent ALI models, in particular, have revealed important biological mechanisms underlying the temporal sequence of injury, inflammation and dysregulated repair.
Soft tissue oedema is seen in the calf Open image in new window Fig. 8 Coronal images of the wrist in a child with active arthritis at the wrist showing high signal within the carpal bones on STIR sequence (a), which enhances on the post-contrast T1 f. sequence (b), indicative of inflammation (arrows).
This network of immune responses is the consequence of the abundance of peptides with significantly conserved sequence homology at the site of inflammation.
Repair of injured tissues occurs as a sequence of events, which includes inflammation, proliferation, and migration of different cell types [ 1].
In an attempt to explain the lack of a significant effect of treatment of periodontal disease during pregnancy on perinatal outcomes, we could speculate that treatment with scaling and root planing does not alter the sequence of events leading from regional inflammation due to periodontitis to systemic inflammation and onset of preterm birth.
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