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However, in the BCS mice the OBF1 transgene is expressed already before EBF1 and this altered sequence of expression compromises the development of the proB cells.
The algorithm matches the sequence of expression levels for each gene against temporal patterns having one or two transitions between two expression levels.
A disruption of the normal sequence of expression of genes that make these organs is responsible for this (Thewissen et al. 2006).
This ordered sequence of expression as a function of Notch activity levels fixes an ordered sequence for the threshold values of the regulatory functions in our modeling approach.
In any case, the history of PfEMP1 expression is recorded in the antibody repertoires that accumulate in individual hosts, regardless of the molecular basis of the sequence of expression [4], [17] [19].
The sequence of expression of the fusion-proteins corresponded to their respective gene expression kinetic class, with IE2-EYFP being detected from 6 hpi, ppUL83-EYFP from 24 hpi and ppUL32-EYFP in the late phase at 72 hpi.
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The sequence of expressions that move across Ms. Gaitanopoulou's face, from abrupt recognition to fear to existential nausea, is almost unbearable.
An interesting sequence of expressions must have crossed his face when he watched "The Simpsons Movie" in 2007: here, in glowing animation, was a great glassy dome landing on a clueless municipality, a civic meltdown, etc. ("We're trapped like rats!" screams Moe the bartender. "No," says the man from the E.P.A., "rats can't be trapped this easily. You're trapped like... carrots").
One cannot prove the claim that every number has a successor simply by producing the sequence of expressions for cardinal numbers (e.g., the second of the two sequences described above).
High-throughput sequencing of expression data provides compelling evidence that the long held hypothesis "one gene produces one protein" is far less common than previously thought.
After obtaining and confirming DNA sequences of expression constructs, the established bacterial clones were cultured and activated with IPTG in order to produce recombinant p53 protein antigen.
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