The interpretation of such diverging strategies can be illustrated from the sequence of data acquisitions of the best performing teams.
Data were gathered using a single shot echo planar imaging (EPI) sequence for data acquisition, with a TR of 3 seconds, a TE of 35 ms and a 90 degree flip angle.
The T1 parameters were repetition time (TR) of 500 ms and an estimation time (TE) of 11 ms. Functional MRI data were gathered using a single-shot echo planar imaging (EPI) sequence for data acquisition, with a TR of 2000 ms, a TE of 50 ms, and a 90-degree flip angle.
This advance was made possible by progressing from traditional Sanger sequencing methods to so-called "next-generation" methods that focused on miniaturization of the sequencing reactions, massive parallelization of data acquisition, and computational analysis.
By computer simulations, we compare the two methods of data acquisition - sequencing each diploid individual separately and sequencing the pooled sample.
On the positive side, simulated data are essentially free, allowing one to determine ahead of time whether a major sequencing effort might be worth the cost of data acquisition.
In fact, peripheral biomarkers are potentially easier and less expensive to analyze, when compared with genome-wide sequencing or brain imaging, which require procedures of data acquisition difficult to apply on a large scale.
DNA Barcoding has greatly influenced the pace of sequence data acquisition.
The advantages of this sequence include fast data acquisition, avoidance of breathing artifacts and complete coverage of the liver in a single breath hold.
The initial sequencing of the human genome was made possible by the automation of the DNA sequencing chemistry and by the development of data-acquisition tools and software for the reliable interpretation and assembly of the DNA sequence.
Instead of projecting laser lines or spots, it projects patterns of a structured light sequence (called Gray Code or Phase Shift sequence) for topometric data acquisition.
