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A sequence of criteria was used to select genes dependent on each DNA methyltransferase.
The decision tree produces a sequence of criteria by which a population is successively subdivided based on intensity values of certain compounds.
SNPs were subsequently discarded using the following sequence of criteria: GenCall score at the 50% rank (50% GC) < 0.40; cluster separation (ClusterSep) < 0.25; more than 5% missing calls.
The reliability of each genotype call was measured using the GenCall score, and SNPs were subsequently discarded using a sequence of criteria in the following order: GenCall score at the 50% rank (50% GC) < 0.40; cluster separation (ClusterSep) < 0.25; more than 5% missing calls; segregation discrepancy.
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Paths represent patient clinical profiles as sequences of criteria.
The objective of this analysis is twofold: (i) examine how some design parameters of the criterion can be used to enlarge the domain of attraction; (ii) examine how the minimization of a sequence of intermediate criteria can possibly lead to the global minimum of the original criterion without the danger of entrapment in a local minimum.
Utilizing the differential inequality strategies, a sequence of sufficient criteria ensuring the global exponential convergence of involved model are presented.
Thus, based on a sequence of selection criteria (publication or not, randomisation to 10% and the final exclusion), 842 QAPs were included in the study.
This is clear through our inability to increase success of sequence comparison criteria through the use of "best close match".
DEQOR evaluates all possible 19mers from the hairpin sequence for a number of criteria (GC content, GC balance across the length of the siRNA and polynucleotide stretches) resulting in a score that reflects the efficiency of each 19mer in RNAi (the lower the score, the better RNAi performance, siRNAs below score 5 are considered suitable for RNAi).
Using a more relaxed set of criteria (sequence identity >80%, size >200 bp), there were 2,450 and 5,103 copies, respectively (Table 1, Additional file 7, 8, Table S4, S5).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com