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Given that these techniques achieve the same surgical result in terms of tissue ablation it is likely that a future laser procedure, which replicates the treatment benefit and low cost of diathermy, could take its place within the sequence of cost effective treatment.
In addition, with the lowering of sequencing costs, the price of such an approach is highly competitive.
One such tool is the MACC (marginal abatement cost curve), used to capture the least-cost sequence of abatement options.
With future reduction of sequencing costs, this approach could ultimately also be used with eukaryotic genomes of larger sizes.
For our illustration, we calculated 95% confidence intervals for a sequence of 10 uniquely spaced cost values.
Overall, our protocol offers comparable data quality but outperforms traditional Sanger sequencing in terms of cost-effectiveness and throughput.
All three billion DNA base pairs of several Holstein bulls have been fully sequenced and costs of sequence data are rapidly declining.
The costs of WES consist of the cost of the capture plus the cost of sequencing, whereas WGS consists only of the sequencing costs.
The availability of the completed human genome sequence and reduced costs of sequencing have allowed large-scale screens to uncover genes that are somatically mutated in cancer.
The past 10 years have witnessed a dramatic reduction of DNA sequencing costs enabled by the emergence of several disruptive sequencing technologies.
That game's protagonist, Niko Bellic, would fret in animated sequences about the costs of his life of violence.
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