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It is possible that even the non-conserved elements may contain a short sequence of conservation that is responsible for enhancing activities, particularly since the typical transcription factor binding site is just a few nucleotides-long.
Referring to the bi-Hamiltonian structure of the Camassa-Holm equation [2], the Camassa-Holm equation has an infinite sequence of conservation laws that insure the existence of the peaked wave during the propagation process.
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Comparison of the proximal promoter sequences revealed high degrees of sequence conservation including conservation of a putative AP1 binding site (Fig. S5).
Initially, the miRNAs have been discovered by direct cloning and sequencing [ 3, 4], which suggested a high degree of sequence conservation of miRNA across species [ 5].
The high degree of sequence conservation of their molecular targets makes a range of these toxins active at human receptors.
In addition, these tools also indicate the details of sequence conservation of adjacent bases together with thermodynamic properties of MMIs.
We next assessed the degree of sequence conservation of AN across monocot and dicot plants including the newly sequenced plant genomes.
No satisfactory explanations for the extreme degree of sequence conservation of exonic UCEs have been suggested.
The highest degree of sequence conservation of monomeric beta-satellites among both species was always found between the two repeat blocks in orthologous position within the DUXY locus.
The degree of sequence conservation of miRNA precursors between related species varies widely (compare e.g. the phastcons tracks for manual5 and locus48, Data S1).
This observation may explain the lack of sequence conservation of these residues among different PRMT members.
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