Your English writing platform
Discover LudwigSimilar(59)
DeRIP is a new software tool developed to predict the original sequence of a RIP-mutated region prior to the occurrence of RIP.
One additional primer pair (IPES0152) detected polymorphic loci across all four RIPs (one locus on LG2 of RIP B, and a second locus on LG5 of RIP A, RIP C and RIP D).
Alternatively, a repeat longer than the least RIP-affected repeat (e.g. resulting from a large sequence insertion into a RIP-affected repeat) may have higher total G C content merely due to its greater length.
The sequence of RIP was identified as YSPXTNF.
That seemed like kind of a rip off".
Thus, RIPcal can be used to identify both the presence and direction of a RIP-like sequence change.
The deRIP process predicts the sequence of the pre-RIP-mutated version of the repeat alignment.
The resultant "deRIPped" sequence is a prediction of what a RIP-mutated repeat DNA may have looked like prior to RIP mutation.
The majority consensus of the non-RIP-affected copies of Y1 were compared to the majority and deRIP consensus sequences of the RIP-susceptible copies as above.
To increase transgene expression, we generated the AAV-mRIP Luc vector with a modified RIP (mRIP) promoter, which has the CMV enhancer sequence upstream of the RIP promoter (Fig. 1A).
A RIP dominance of greater than 0.6 by comparison to the repeat with highest G C content was considered a reliable threshold for RIP [ 20].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com