Taken together, these findings strongly suggest that, the extreme sequence divergence notwithstanding, arCOG05692 proteins are bona fide RecJ orthologs with an inactivated DHH domain.
It should be noted that, the high sequence divergence notwithstanding, the secondary structure profiles are closely similar for all four amalgaviral CPs (Additional file 3: Figure S3).
Their generally high plasticity and poor sequence conservation notwithstanding, lncRNAs are emerging as an important and novel transcriptional regulatory mechanism that is likely to significantly impact beta cell fate and function.
We report that the atomic interaction network in the solvent-unexposed core of protein domains are fold-conserved, extraordinary sequence divergence notwithstanding.
Rapidly evolving phage ORFans are thought to supply many, if not most, of the ORFans found in prokaryotic genomes (the lack of detectable sequence conservation notwithstanding), hence playing an important role in evolution of prokaryotes [ 12]. aThe classification is based on the analysis described in [87].
Notwithstanding low sequence identity (60%), GIMFhelix is functionally an isoenzyme of GST A4-4.
Notwithstanding, future sequencing efforts, ideally utilizing a combination of short- and long-read sequencing methods, will be needed to resolve the incomplete genes models within both R. felis str.
Rapid advances in next-generation sequencing technology notwithstanding [ 2, 48], aCGH provides an effective alternative to de novo sequencing of a large number of complex eukaryotic genomes.
In this latest sequence, low scores notwithstanding, they have gained a first-innings lead four times, winning three with five draws, losing just three times.
Notwithstanding their primary sequence differences, all enzymes belonging to this superfamily possess the three-domain fold and behave similarly in terms of domain movements upon substrate binding and catalysis.
