Sentence examples for sequence mutation status from inspiring English sources

In the present study we have compared the DNA sequence mutation status of the genes KRAS, BRAF, PIK3CA, PTEN, and TP53 in tumor samples from patients younger than 50 years at diagnosis and without known hereditary syndromes, and stratified according to MSI status and elderly CRC patients.

A meta-analysis of p53 mutation databases has demonstrated methodological biases associated with sequence-based mutation status [ 21].

In our training data set (Sorlie et al)., the gene expression classifier had 82% agreement with sequence-based mutation status.

Previous work has identified only a subset of elements likely to be active, due to genomic position, sequence mutation, or methylation status [ 13].

By cDNA sequencing, we confirmed the mutation status of the cell line and also that the mutant gene is indeed expressed (Figure 3A).

The PCR products of the miR-139 locus were sequenced to analyze the mutation status of miR-139.

Both direct sequencing and Scorpion ARMS allowed mutation status to be determined in the serum samples of all patients.

In the present study, we have analysed a series of CLL cases for VH mutation status by sequencing of the clonal rearrangements, for telomere length by Southern blotting and for clinical outcome.

Including as much as possible DNA template for more reliable sequencing results [44] would perhaps help in less fragmented samples, while discrepant results on KRAS mutation status assessed with sequencing and with DxS-KRAS have recently been reported although not defined [51].

Sixty-one mCRC tumours were analysed for AURKA-CN using q-PCR, and KRAS mutation status by direct sequencing.

Complete sequencing data for ARID1A and PIK3CA mutation status, and BAF250a expression by IHC were available on 90 of the 127 original cases used for proteomic analysis.