These data suggest that transcription factor binding to the EBox sequence is more important to mediate the effect of AMPK activation, but also suggest the fact that GATA could modulate the AMPK effect on DNA binding in regulating the activity of the promoter.
Given the recent recognition of many important additional roles that RNAs play in cellular functions, predicting the common structural features of a set of RNA sequences is more important than ever.
Early studies indicated that TCR diversity correlated with viral control, but more recently these findings have been countered with reports that public TCR sequences are more important and are a superior predictor of patient response to HIV infection.
There are brief lines of dialogue in the "Spellbound" dream sequence, but its more important elements are visual, as in most dreams.
The ghost children who never were get their major moment in Burnt Norton but are reprised in a few lines of Little Gidding; other poems of Eliot engage in metonymy of other texts, and so do these, but here echoes of other poems in the sequence are even more important.
In the wild, the ability to make good decisions in sequence may be more important to a starling, which generally walks through short grass in search of prey, digs into the soil with its bill and then decides whether the site is worth pursuing.
From Table 2, it is clear to see that N-terminal amino acids in the peptide P sequence may be more important to stabilize the helical structure since the relative helicity values of peptide K7D/K14D (71.7%) and L6D/L12D (73.1%) were lower than those of the peptide K14D/K22D (81%) and L12D/L20D (75.7%) respectively.
If the sequence coverage is more important than computational time savings, softer parameters can be chosen, for example with an intensity threshold of s = 25%.
Their aim was to distinguish between two alternatives: Either the increase of the number of intervals in the first sequence (S) is more important (to build a more reliable memory trace), or the increase of the number of intervals in the second sequence (C) is more important (to improve the comparison process).
These sequences steadily become more important in daily clinical use given the strongly increasing rates of worldwide prosthesis implantations and of health issues in an aging population.
