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In light of these previously reported data and the nature of the CRF01_AE sequence, it would be interesting to determine whether TW10 is sufficient to protect B*57/*5801-positive subjects from disease progression.
The repeat is a triplet motif, and if it occurs within a protein-coding sequence, it would stand for either arginine (Arg), lysine (Lys) or glutamine (Glu).
If the observed RNA motif is truly a pan-like sequence, it would be the first discovery of this RNA family in Actinobacteria.
Therefore our model suggests that once a ribosome was bound to this sequence it would rarely detach from the RDS, while unbound RDS regions would be dynamically driven to the unfolded state in order to resolve their disequilibrium.
Since other members of miR-2 family share the same seed sequence, it would be interesting to determine whether dMyc is under repression by other members of miR-2 family.
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In 1998, SWISSPROT announced that, because its public funding could not keep up with the growing number of sequences, it would charge a yearly license fee to commercial users.a.a
If the 1.7 million Americans who will get cancer in 2016 were to have their healthy and tumor cells sequenced, it would yield one exabyte (1018) of raw data.
With the advent of High-Throughput Sequencing, it would be possible to investigate Single Nucleotide Polymorphisms that potentially change the amino acid sequence if they are non-synonymous.
In order to detect the least abundant candidate (Myt1; 1.3×10−4% of the screened cDNA library) by cloning and sequencing, it would have been necessary to analyze at least 1.0×106 clones.
Due to the limited sources of homologous protein sequences, it would be difficult to build multi-gene trees.
Assuming that the decoy database comprised reversed sequences, it would be expected that none of the peptide hits found there would be real.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com