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To confirm the length of CAG repeat sequence in mice, PCR-based Southern blotting was carried out by primers f1 (5'-CTGAAGTTCATCTGCACCAC-3') and r2 (5'-CTACAAATGTGGTATGGCTG-3') (Fig. 1A), using a labeled (CAG 10 probe as described previously [63].
Zhou and colleagues [ 34] demonstrated that ER does not directly regulate the Muc1 promoter sequence in mice.
In this regard, it might be interesting to determine whether there is a selective pressure against bacterial species that carry the ISR23 sequence in mice but not in human.
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In silico analysis of OPN protein sequences identified four potential PC5/6 consensus cleavage sites in human OPN, and three sites – including a noncanonical sequence – in mouse OPN.
We scored a sequence as having a new TE if the mouse sequence contained a TE that was absent in rat and the genomic alignment had a gap in the rat sequence that matched the length of TE sequence in mouse, and vice versa.
Primers recognized sequence in mouse (endogenous) Crym and recombinant Crym-HA after viral infection.
There is also a single Pgam5 retroposed sequence in mouse in addition to multiple retroposed sequences for Pgam1 in both species.
Since the ED-B domain of fibronectin has an identical sequence in mouse and man, they suggested clinical utility for the scintigraphic detection of angiogenesis in vivo [ 70].
We were able to identify the complete protein sequence in mouse, dog (643 amino-acids, >78% PSI), chimpanzee (99% PSI), frog (38.7% PSI) and zebrafish (23.5% PSI), and partial sequences in chicken (>32% PSI).
The role of TPA-S1 in tumor promotion is suggested by the expression of this sequence in mouse skin carcinomas induced by dimethyl-benzanthracene-TPA treatment, but not in papillomas or in control tissue.
Using pair-wise comparisons, putative CREs from our survey in the human genome were checked for conservation of the motif sequence in mouse, rat and dog using the "LiftOver" tool [ 31, 32].
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