The parameter ν can be determined from protein sequence, an imperative given the scarcity of structural information relative to proteome sizes.
Clarification of the octomer repeat sequence was imperative not only for the correct identification of younger CR1 elements but also for the precise determination of the boundary between CR1 and pre-integration sequences.
Therefore, steps to reduce the amount of exogenous DNA-based contamination prior to sequencing are imperative and are especially relevant when working with unknown viral isolates.
For example, Praamstra and colleagues [10] demonstrated that neural activity during presentation of temporally regular sequences of imperative stimuli (i.e. implicit timing), resembled the neurophysiological correlates of an explicit timing task [21], [22].
We asked whether the implicit use of timing to predict stimulus onset and therefore speed up the detection of temporally regular sequences of imperative stimuli, entailed an internal representation of time and, if so, whether this representation had the same psychophysical properties as that required for explicit timing tasks.
Further studies of the genomic landscape of DCIS and IBC by aCGH (comparative genomic hybridization) and massively parallel sequencing are imperative for clarifying the genomic and genetic alterations involved in DCIS progression and discriminating the more aggressive phenotypes.
As long as finished sequences are not imperative, 454 sequencing can provide advantages in cost and time over classical ABI-Sanger sequencing.
Database URL: http://libaio.biol.mcgill.ca/lps-annotate.html Development of tools for automated biological-sequence annotation is imperative, particularly since now greater than 1500 complete genomes have been sequenced and assembled.
With so many genomes to be sequenced, it is imperative that laws and policy ensure that individuals, and society, are protected from harm.
With the identification of new coding and regulatory sequences, it is imperative that microarrays be updated to enable more complete expression profiling of genomes.
Based on this experience, we felt that the selection and utilization of essential resources to systematically manage and disseminate the considerable amounts of data generated by these sequencing projects was imperative.
