Exact(2)
Our sequence findings are consistent with developmental data that we and other labs have presented showing that B-1a and B-2 cells belong to evolutionarily distinct B lineages.
Indeed, accurate and complete clinical information is so essential for the interpretation of genome-level DNA sequence findings that the laboratory can reasonably refuse to proceed with the testing if such information is not provided with the test sample.
Similar(58)
Though there exist many different approaches to signal (i.e. short sequence) finding, some new study shows that this problem still leaves plenty of room for improvement.
In addition, even when ODN uptake into the nucleus occurs, the efficiency of correction remains low, due to difficulties in having the correcting sequence finding its homologous target and being substituted into the cellular genome.
Lastly, the same set of Solanum BAC sequences was searched with the de novo repetitive sequence finding algorithm, RepeatScout [ 73].
Sequences were processed and assembled by using the Staden package [ 62] with the repeat sequence finding module TROLL [ 63] and Primer3 [ 64].
Genome-wide association studies have also highlighted the evolutionary significance of noncoding sequence, finding as much as 88% of trait-/disease-associated variants lies in noncoding sequence (Altshuler et al. 2008; Hindorff et al. 2009).
For repetitive sequence finding, all model organisms were used from RepBase, the TREP11_beta database was used as the organism specific repeat library and the te_proteins.fasta file provided with Maker was also used.
Whole-exome sequencing findings were confirmed by massively parallel sequencing.
The serologic data support PCR and sequencing findings.
The raw data from genome-wide association-studies, such as ours, can provide a powerful tool with which upcoming sequencing findings could be more successfully interpreted.
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