CpG oligodeoxynucleotides (ODNs) show strong immune stimulatory activity in vertebrate, however, they possess specific sequence feature among species.
Using these QSARs, a new group-specific sequence feature of WW domains that target arginine-containing peptides was identified.
IT sequence feature extraction enables the distinction among species and is less computationally expensive than motif calculations.
When evaluated by independent data testing, ensemble based-bagging algorithms with sequence feature composition, transition and distribution (CTD) successfully classified two datasets with accuracies greater than 90%.
The PCA plots between PC1 and PC2 for each sequence feature was studied (Figure 3).
On the other hand, it also suggested dependence for divergent sequence feature on differential exon splicing.
The SAAR distributions are a simple sequence feature that potentially can be used in proteome comparison.
Nevertheless, this unique sequence feature creates an irregularity in the coiled-coil structure.
We thus designed our study without any bias towards a particular sequence feature.
This finding indicates that the predicted solvent accessibility is a very important sequence feature that contributes significantly to the performance improvement when combined with other features.
With respect to the local sequence feature extraction, a sliding window method was used to capture the sequence environment [27], [42].
