Sentence examples for sequence environments from inspiring English sources

The structure and flexibility of the RNA duplex has been studied using extended molecular dynamics simulations on four diverse 18-mer oligonucleotides designed to contain many copies of the 10 unique dinucleotide steps in different sequence environments.

As with other currently used mtDNA typing methods such as sequencing analysis of multiplexed short PCR products, hybridization probe based assays, or minisequencing, successful assay designs might be challenging or even impossible for particular sites in such "unstable" sequence environments.

An additional Tn3 family member of 26712 bp carrying an operon of 23 ORFs, which include heavy metal resistance genes, is found as identical copies in all three Arthrobacter sp. FB24 plasmids in different sequence environments.

The results suggest that residue depth could be reliably predicted solely from protein primary sequences: local sequence environments are the major determinants, while global sequence features could influence the prediction performance marginally.

Plasmids may be integrated into the genome and thereby the plasmid sequences can be present in the assemblies surrounded by two different sequence environments (plasmid only sequences or adjacent genome parts), making the integration site a low coverage region.

Considerable progress is also made in the development of novel types of oligonucleotides allowing successful primer design in e.g. AT-rich sequence environments (e.g. [58]) and the incorporation of nucleotide analogues into allele-specific primers was shown to further increase their allele-discriminatory potential (e.g. [59]).

Consequently, a mirror image sequence environment has been established by mirror image algorithm.

It therefore demonstrates the neighboring sequence environment is helpful for determination of cleavage site.

Then, based on an estimated hydrophobic h-region a correcting function is proposed to improve the prediction result, in which the sequence environment is taken into account.

It is reported that the cleavage site has relationship with the neighboring sequence environment, i.e., hydrophobic core h-region, and the specific patterns in c-region.

However, in these models, sequence environment information is merely taken account of as model inputs and no detailed investigation into its effect on the prediction of cleavage site has been made.