It follows from these observations that pure sequence difference among different samples generated by SM-LATE-PCR must have been present in the initial population of molecules.
The better explanation for Mh65 could be that the sequence difference at the loop part of hairpin makes Mh65's structure differ from gga-mir-33-2's.
Even a single sequence difference can explain significant differences in ligand-binding affinities between two receptors.
There were indications of a sequence difference between Hwayeong and its anther culture derived progenies.
However, no sequence difference was found among the five genotypes (Habataki, ST12, NSIC Rc158, NSIC Rc222, and NSIC Rc238).
16S rDNA-PCR primers were designed based on the sequence difference in variable regions of B. cereus 16S rDNA and B. thuringiensis 16S rDNA.
In ORF2 (viral nucleocapsid gene) archival PCV2, a consistent linear nine-base sequence difference at base positions 1331 through 1339 was observed.
We improve the GRA by introducing variation rate into the calculation of sequence difference, which enhances the correlation degree between indicators.
It remains a question if the difference in protein structure, represented by this sequence difference could result in the differences observed in binding affinity.
The average sequence difference between the three O. emmonsae studied was 0.8%.
(2) Percent sequence difference calculated using a program we developed, psi-distance, available at http://tornado.igb.uiuc.edu/.igb.uiuc.edu/
