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When multiple isoforms were present, we removed all but one representative sequence based on the following criteria.
In essence, this variability is the product of the number of different nucleotides that are observed at any given sequence position and represents the maximum number of different combinations one might expect to sequence based on the observed variation.
Mappability is a measure of the uniqueness of a given genomic sequence based on the number of sequenced fragments uniquely alignable to that sequence.
We then aligned this structure-based alignment to the human UGT1A1 sequence based on the predicted vertebrate UGT secondary structure profile.
The first, substructure keys-based fingerprints, set the bits within a molecular fingerprint bit sequence based on the presence or absence of predefined structural features.
For a proper comparison of MRI patterns in a masked sequence, one should compare it to the SRI-generated random sequence based on the masked sequence.
For patients in arm B, intravenous meropenem can be switched to one of the following oral drugs in the specified sequence, based on the susceptibility tests.
Celera will make public a reference DNA sequence based on the genomes of all these individuals.
Select a 21nucleotide sequence based on the algorithm of Vert et al. (2006).
It incrementally adapts, merges and splits segments along a sequence based on the coherence of motion information within each segment.
Our technique computes HDR video zones which are constant throughout a sequence, based on the luminance of each pixel.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com