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Replacement of the Beaudette S gene with the corresponding M41 S gene sequence altered the tropism of the rIBV but did not result in a change in virulence [24] [26].
Moreover, a 3′ mutation in the human miR-499 sequence altered the expression of different cardiac-specific mRNAs [ 46].
However, the linker is not expected to affect aptamer folding or target binding and may be moved to the 5′ end or have its sequence altered with a corresponding change in the DNA linker.
Although rearrangements of nucleotides downstream of one of the editing sites in the maize rps12 mitochondrial mRNA did not affect the editing, similar rearrangements at another editing site within this sequence altered editing, suggesting that each editing site has different cis-elements at different positions.
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Moreover, unsent silence parts of a given speech sequence alter the initially generated packet loss pattern.
A cyclic sequence altering breaths with expiratory holds with normal breaths induces periodic changes in alveolar concentration of carbon dioxide.
In the presence of the released sequence, the binding between the dye-labeled DNA and the SD sequence alter the conformation of dye-labeled DNA, and disturb the interaction between the dye-labeled DNA and GO, liberating dye-labeled DNA from GO.
In other cases polymorphisms in the gene sequence alter the apparent expression level of some probes.
Point mutations within this sequence alter CD44 transcription (Zhang et al, 1997).
c.[749delT] is predicted to result in a frameshift in the nucleotide sequence altering the next six amino acid residues (246GSTQVGKQ253 … → 246GSTQGENRWA255X) prior to introducing an inframe stop codon.
The "Fluctuating Neutral Space" model of Takahata (1987) posits that nearly neutral changes to the protein sequence alter the subsequent rate of nearly neutral substitution, leading to overdispersion.
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