Sentence examples for sequence abnormality from inspiring English sources

To further characterize the splicing events around this sequence abnormality we performed a minigene splicing study.

The second sequence abnormality was a homoplasmic point mutation in the D-loop; G-A at nucleotide 16 129 in HVS1.

After execution, as shown in Figure 5A, AFST is able to provide a tabular result showing final clean, trimmed sequences and information about sequence abnormality such as DBT and RECA.

While it is well established that specific DNA sequence abnormalities are linked to smoking status, other oncogenomic events are less well known among never smokers.

Potential sequence abnormalities that were identified by using the phylogenetic approach [30], [31], as performed manually and/or automatically by the MitoTool (http://www.mitotool.org; this software was designed by ourselves), were rechecked for the original sequencing electropherograms or resequencing.

Although residual amounts of abnormally spliced Pink1 transcript would exist in all these Pink1 mutant mouse lines and it could be speculated that residual amounts of PINK1 protein with abnormal 3' sequences are relevant, it is highly probable that mouse phenotypes would result from the engineered deficiency rather than from sequence abnormalities of residual PINK1.

DNA sequence abnormalities and co-segregation in families were confirmed by restriction endonuclease analysis (New England Biolabs), as described (11).

DNA mutation detection databases All cancers arise as a result of the acquisition of a series of fixed DNA sequence abnormalities.

In this study, we have adopted a novel pattern analysis approach that proves to be effective in identifying and distinguishing EST sequence abnormalities based on cDNA termini structures.

In our experience, old and poorly stored DNA samples often yield false-positive sequence abnormalities in high-throughput sequencing because of degradation of the DNA and whole genome amplification does not rectify this.

After random correction, three restriction fragments were removed that returned aberrant values (HoxD: chr2:74'597'000-74'597'732; cHoxB74'608'796-74'609'312, HoxB: chr11 95'999'958-96'000'916) due to sequence abnormalities in the BAC template (confirmed by Sanger sequencing; not shown).