The chronic hyperglycemia that characterizes type 2 diabetes is related to a significant long-term sequelae, including damage to and eventual failure of various organs (macrovascular), and directly related to the likelihood of developing microvascular complications (8).
Other reported sequelae included ocular damage (2), xerostomia (2), chronic sinusitis (2), damage to permanent teeth (1), loss of the sense of smell (1), and behavioral disorders (1).
Furthermore, 346 patients with the following diagnoses were excluded: rotator cuff arthropathy (n = 109), sequela after ligament damage (n = 39), sequela after dislocation (n = 21), psoriatic arthritis (33), ankylosing spondylitis (21), osteonecrosis (n = 24), sequela after infection (n = 19), and other diagnosis (n = 80).
The patient was discharged from the hospital 2 days after surgery, he immediately started a physical therapy program and he returned to school after 2 months of therapy without sequelae or neurologic damage.
The rationale for preserving these nerves during surgery is to avoid the well-known sequelae of nerve damage, such as impaired bladder function [2], rectal motility disorders and sexual dysfunction [3, 4, 5].
Although nicotinamide has been confirmed to decrease infarct volumes and neurological deficit findings in several animal stroke models, it is not clear whether its neuroprotective effects can prevent memory damage sequelae.
Early diagnosis of leishmaniases is vital to avoid permanent damage, sequelae, and even death, depending on the disease form.
Targeting immune checkpoints with mAbs is associated with auto-immune sequelae and inflammatory damage to normal parenchyma.
Potential sequelae are mucosal damage, loss of barrier function, bacterial translocation, systemic inflammation, multiple organ failure and death.
It has been suggested that the changes in subchondral bone may be the initiating factor in the pathogenesis of OA rather than sequelae of cartilage damage [ 15].
