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This effect arises due to the gradual separation of cells representing different locations into separate theta phases, as seen explicitly in Figure 3C,D.
Affinity-based magnetic methods similar to that seen for the separation of cells have also been used for separating proteins, DNA and ribonucleic acid (RNA) from nutrient media, fermentation broths, tissue extracts and biological fluids [ 99].
In addition, the separation of cells is important in the biotechnology industry.
If no archenteric cavity is formed during gastrulation, the cavity of the alimentary canal is formed by the separation of cells in the middle of the mass of endoderm (as in bony fishes) or by folding of the sheet of endoderm.
Separation of cells and particles using magnetic forces is called magnetophoresis.
Immunomagnetic-based separation has become a viable technique for the separation of cells and biomolecules.
Lastly, ferrofluids can be used to "push" and "pull" cells enabling label-free manipulation and separation of cells and bacteria.
These advancements provide a good opportunity for development of novel separation techniques, the so-called optophoresis, which use optical forces for separation of cells and particles.
Novel methods and devices for positioning and subsequent separation of cells are used in the medical environment for on-chip analysis of human cells [1].
We engineered a novel HIV-1-based reporter virus called NL4-3-IRES-HSA thallowsows for the magnetic separation of cells infected with fully competent virions.
This separation of cells and MNPs within magnetic cellular spheroids was successfully incorporated into cellular spheroids with various cellular and extracellular compositions and contents.
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