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Analyses for cumulative incidence and risk factors were conducted for the whole cohort as well as separately for secondary acute myeloid leukemia/myelodysplastic syndromes (AML/MDS) and secondary solid tumors (including new lymphomas).
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Analogous to the primary analysis, mixed models were fitted separately for the secondary endpoints in groups 1, 2 and 3.
For the elementary school univariate analysis was performed separately for primary and secondary cases.
Information about discontinuation rates is scarce, and no previous study has described discontinuation rates in the general population separately for primary and secondary prevention.
We will do this separately for the 28 secondary and 319 primary circular chromosomes; the 5 linear chromosomes will not be analyzed in this section.
Stroke, systemic embolism, cardiac death, and all-cause death were assessed separately and in combination for secondary end points.
In Finland, cases of failed osteosyntheses are not recorded separately but as other reasons for secondary osteoarthritis.
The primary composite endpoint and its components were analysed separately for the primary and secondary prevention cohorts.
Relative risks of TB by year of diagnosis, age, sex, and Dutch or non-Dutch nationality were determined separately for new strains and secondary cases with Poisson regression.
We also additionally adjusted M2 for DCCT treatment group and separately for DCCT prevention cohorts in secondary analyses.
To look at this result in more detail we analyzed the individual and mean effect of the secondary insertions separately for each disruption strain (data not shown).
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